The corium is located under the epidermis and isa well supplied with blood, connective tissue, which ensures the supply of the epidermis with nutrients. It is interspersed with sensory and vegetative nerves. The dermis consists of 2 – 4 % elastin fibres, which form an elastic network in the skin. From the age of 30 onwards, the production of these fibres is reduced, which later leads to saggy aged skin.
The dermis also contains mast cells which collect substances such as histamine and serotonin. They are the effector cells of immediate allergic reactions and are involved in inflammatory reactions.